Hep C Reinfection Low Among People Receiving Opioid Agonist Therapy
MONDAY, Aug. 8, 2022 (HealthDay News) -- Reinfection with hepatitis C virus (HCV) is low after successful treatment among people receiving opioid agonist therapy (OAT), according to a study published online Aug. 9 in the Annals of Internal Medicine.
Jason Grebely, Ph.D., from The Kirby Institute in Sydney, and colleagues examined the rate of HCV reinfection for three years after successful treatment among people receiving OAT at 55 clinical trial sites in 13 countries. A total of 199 participants aged 18 years and older with chronic HCV infection with genotypes 1, 4, or 6 receiving stable OAT were enrolled in the long-term extension study.
The researchers found that the rate of HCV reinfection was 1.7 per 100 person-years. People with recent injecting drug use had a higher rate of reinfection (1.9 per 100 person-years). At the six-month follow-up, 59 and 21 percent of participants reported ongoing drug use and injecting drug use, respectively, which remained stable during three years of follow-up.
"Reinfection with HCV was highest in the period immediately after treatment and among people with ongoing injecting drug use and needle-syringe sharing," the authors write. "Further research is needed on interventions to retain populations of people who inject drugs in care and ensure that either HCV reinfection can be prevented or that reinfections can be detected quickly with retreatment to prevent the risk for transmission to others."
The study was funded by Merck Sharpe & Dohme Corp.
Abstract/Full Text (subscription or payment may be required)
Related Posts
¿Le encantan el café y el chocolate negros? Quizá se deba a su ADN
JUEVES, 30 de diciembre de 2021 (HealthDay News) -- Si le gusta el café negro,...
Un nuevo tratamiento para la EM se muestra promisorio en un ensayo
JUEVES, 25 de agosto de 2022 (HealthDay News) -- Una terapia experimental de...
COVID-19 Pneumonia Hospitalization Tied to New-Onset Dementia
MONDAY, May 2, 2022 (HealthDay News) -- Approximately 3 percent of patients with...
AHA News: New Year, Healthier You? Here’s How to Gradually Improve Your Eating Patterns
FRIDAY, Jan. 6, 2023 (American Heart Association News) -- Losing weight is a...