Exercise May Lower Clotting Risk in Patients With NASH

TUESDAY, March 8, 2022 (HealthDay News) -- Exercise may help patients with nonalcoholic steatohepatitis (NASH) reduce their risk for developing blood clots, according to a study recently published in Hepatology.
Jonathan G. Stine, M.D., from Pennsylvania State University in Hershey, and colleagues randomly assigned patients with biopsy-confirmed NASH to either an exercise training program (18 patients) or standard clinical care (10 patients).
The researchers found that the plasminogen activator inhibitor 1 level was significantly decreased with exercise training versus standard clinical care (−40 versus +70 ng/mL). Exercise training was also associated with decreased magnetic resonance imaging proton density fat fraction (MRI-PDFF), with 40 percent of exercise participants having a ≥30 percent relative reduction in MRI-PDFF (histological response threshold) versus 13 percent among those receiving standard of care. Lastly, exercise training was associated with improved fitness (as measured by VO2 peak) versus standard clinical care.
"Independent of weight loss or dietary change, exercise training resulted in a significantly greater decrease in thrombotic risk than standard clinical care in patients with NASH," the authors write.
One author disclosed financial ties to the pharmaceutical industry.
Abstract/Full Text (subscription or payment may be required)
Related Posts
4.5 Percent of U.S. Adults Used Electronic Cigarettes in 2021
FRIDAY, July 21, 2023 (HealthDay News) -- In 2021, 4.5 percent of U.S. adults...
Las tasas de suicidios y homicidios siguen aumentando entre los jóvenes de EE. UU.
JUEVES, 15 de junio de 2023 (HealthDay News) -- Los suicidios y los homicidios...
¿Dar el seno podría ayudar a las mujeres a conservar su inteligencia con la edad?
JUEVES, 28 de octubre de 2021 (HealthDay News) -- ¿Podría la lactancia materna...
Warning Labels on High-Powered Magnets Unlikely to Prevent Child Injuries
MONDAY, Oct. 3, 2022 (HealthDay News) -- Parents of children with high-powered...