Thickness of GCIPL, INL of Retina Reduced in Parkinson Disease
THURSDAY, Aug. 24, 2023 (HealthDay News) -- Reduced thickness of the ganglion cell-inner plexiform layer (GCIPL) and inner nuclear layer (INL) of the retina are seen in individuals with Parkinson disease (PD), according to a study published online Aug. 21 in Neurology.
Siegfried Karl Wagner, M.D., from the University College London, and colleagues used data from a retrospective cohort of 154,830 patients aged 40 years and older from the AlzEye cohort to detect retinal markers, measured using optical coherence tomography, in prevalent PD from 2008 to 2018. In addition, retinal markers were examined in incident PD using data from 67,311 volunteers aged 40 to 69 years from the U.K. Biobank who underwent retinal imaging during 2006 to 2010.
The researchers identified 700 patients with prevalent PD and 105,770 controls within the AlzEye cohort. Thinner GCIPL and INL were seen for individuals with prevalent PD (–2.12 and –0.99 µm, respectively). Fifty-three participants from the U.K. Biobank developed PD at a mean of 2,653 ± 851 days. Associations were seen for thinner GCIPL and thinner INL with incident PD (hazard ratios, 0.62 per standard deviation increase and 0.70, respectively).
"I continue to be amazed by what we can discover through eye scans. While we are not yet ready to predict whether an individual will develop Parkinson's, we hope that this method could soon become a pre-screening tool for people at risk of disease," Wagner said in a statement.
Editorial (subscription or payment may be required)
Related Posts
Online Programs, Phone Apps Can Help Treat Depression
TUESDAY, Dec. 14, 2021 (HealthDay News) -- People with depression symptoms might...
AHA News: Los ‘héroes’ de la reanimación cardiopulmonar necesitan más apoyo, señala un informe
LUNES, 21 de marzo de 2022 (American Heart Association News) -- Cuando ella...
Anabolic Steroids
What are anabolic steroids?Anabolic steroids are a class of synthetic drugs that...
AHA News: 8 Days After Giving Birth, 29-Year-Old Had a Stroke
THURSDAY, June 30, 2022 (American Heart Association News) -- Noelia Gutierrez...