Buprenorphine-Naloxone Appears Safe for Maternal Opioid Use Disorder
FRIDAY, Jan. 13, 2023 (HealthDay News) -- Buprenorphine-naloxone seems to be as safe for pharmacotherapy for maternal opioid use disorder as buprenorphine monotherapy, according to a study published online Jan. 11 in Acta Obstetricia et Gynecologica Scandinavica.
Minna M. Kanervo, from the University of Helsinki in Finland, and colleagues followed 67 pregnant women on medical-assisted opioid maintenance treatment from conception to delivery to compare the outcomes of the pregnancies, deliveries, and newborns.
The researchers found that the buprenorphine-naloxone and buprenorphine groups showed similar outcomes and did not significantly differ from each other in terms of maternal health during pregnancies, deliveries, or newborns. Among all groups, illicit drug use during pregnancy was common, but in the methadone group it was most prevalent. The vast majority of neonates (96 percent) were born full-term with good Apgar scores. Newborns had relatively small birth size, with those in the methadone group tending to be the smallest. Nearly two-thirds of the neonates (63 percent) needed pharmacological treatment for neonatal opioid withdrawal syndrome, with lower need seen in the buprenorphine-based groups versus the methadone group.
"Combination therapy of buprenorphine and naloxone could be a choice for oral opioid maintenance treatment during pregnancy, but larger studies are needed before changing the official recommendations," Kanervo said in a statement.
Related Posts
CRC Risk Modestly Reduced for Those Invited to Screening Colonoscopy
TUESDAY, Oct. 11, 2022 (HealthDay News) -- Participants who are invited to...
¿Por qué las mujeres negras tienen más retrasos en unas biopsias del seno que salvan vidas?
MARTES, 28 de junio de 2022 (HealthDay News) -- Las mujeres de color podrían...
United States Exceeds Western Europe for Excess Deaths
THURSDAY, March 30, 2023 (HealthDay News) -- The United States had a marked...
STD Cases Soar in US Amid Calls for Better Prevention Efforts
TUESDAY, Sept. 20, 2022 (HealthDay News) – Soaring numbers of sexually...