Weight Loss in Adulthood Tied to Reduced Risk of Colorectal Adenoma
TUESDAY, Feb. 1, 2022 (HealthDay News) -- Weight loss in adulthood is associated with reduced risk of incident distal colorectal adenoma, according to a study published online Feb. 1 in JNCI Cancer Spectrum.
Shishi He, from the University of Maryland School of Medicine in Baltimore, and colleagues assessed weight change during early-late (age 20 to baseline [55 to 74 years]), early-middle (20 to 50 years), and middle-late (50 to baseline) adulthood in relation to incident distal adenoma in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (1,053 cases and 16,576 controls).
The researchers found that weight loss during early-late adulthood was associated with reduced adenoma risk compared with stable weight (odds ratio, 0.54; 95 percent confidence interval [CI], 0.34 to 0.86), especially for those who were overweight or obese at age 20 (odds ratio, 0.39; 95 percent CI, 0.18 to 0.84). Similar results were seen for early-middle adulthood, but were less pronounced for middle-late adulthood. Increased risk was seen in association with weight gain of more than 3 kg in five years during early-late adulthood (odds ratio, 1.30; 95 percent CI, 1.07 to 1.58). The findings were stronger for men (odds ratio, 1.41; 95 percent CI, 1.11 to 1.80) than for women (odds ratio, 1.09; 95 percent CI, 0.79 to 1.50).
"Based on our findings, we would not recommend weight loss for all adults," a coauthor said in a statement. "But the results suggest that overweight and obese adults may benefit from weight loss."
Related Posts
Un estudio refuta la teoría de que las personas con depresión son solo más ‘realistas’
VIERNES, 14 de octubre de 2022 (HealthDay News) -- Algunas personas creen en la...
It’s a Win-Win When a Child With Autism Gets a Shelter Cat
FRIDAY, Sept. 10, 2021 (HealthDay News) -- Parents of a child with autism might...
Men More Prone to Cancer Than Women, But Why?
WEDNESDAY, Aug. 10, 2022 (HealthDay News) -- Men are known to be more likely to...
Depression Rates Rise for Minority Youth in States With Anti-LGBT Legislation
WEDNESDAY, July 5, 2023 (HealthDay News) -- Youth who are both LGBTQ+ and either...