Treatment for Common Rotator Cuff Ailment May Be Useless
THURSDAY, Oct. 12, 2023 (HealthDay News) — Treating shoulder pain with steroid shots or removal of cartilage buildup yields the same result as no treatment at all, a Norwegian research team reports.They said their findings call into question treatmen…
Learn MoreTeen Surgery-Linked Opioid Prescription Rates Stable From 2015 to 2020
TUESDAY, Oct. 10, 2023 (HealthDay News) — For U.S. adolescents, there was a decrease in opioid prescription rates from 2015 to 2020 for nonsurgical indications, but opioid prescription rates associated with surgery remained stable, according to a res…
Learn MoreMost Who Get Heart Valve Replacement Don’t Get Follow-Up Rehab
TUESDAY, Oct. 10, 2023 (HealthDay News) — A majority of people who have a minimally invasive heart valve replacement procedure are not getting the recommended cardiac rehab after their surgeries, researchers say. A new study finds that just under 31%…
Learn MoreGemcitabine, Cisplatin, Nivolumab Facilitate Bladder Sparing
WEDNESDAY, Oct. 4, 2023 (HealthDay News) — For patients with muscle-invasive bladder cancer (MIBC), treatment with gemcitabine, cisplatin, plus nivolumab facilitates bladder sparing, according to a study published online Oct. 2 in Nature Medicine.
Matthew D. Galsky, M.D., from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues conducted a phase 2 study of 76 patients with MIBC who received four cycles of gemcitabine, cisplatin, plus nivolumab followed by clinical restaging. Patients who achieved a clinical complete response (cCR) could proceed without cystectomy.
Of the patients, 33 achieved a cCR (43 percent); 32 of the 33 opted to forgo immediate cystectomy. The researchers found that the positive predictive value of cCR for a composite outcome of two-year metastasis-free survival in patients forgoing immediate cystectomy or ATM, RB1, FANCC, and ERCC2) or increased tumor mutational burden. There was an association noted between the baseline and on-treatment immune contexture with clinical outcomes.
“Treatment for muscle-invasive bladder cancer is in need of major improvements from both a quality-of-life and an effectiveness standpoint,” Galsky said in a statement. “If additional research confirms our findings, this may lead to a new paradigm in the treatment of muscle-invasive bladder cancer.”
Several authors disclosed ties to the biopharmaceutical and medical technology industries.
Learn MoreShorter Course of Radiation May Be Safe for Women Undergoing Breast Reconstruction
WEDNESDAY, Oct. 4, 2023 (HealthDay News) — Breast cancer patients who undergo a mastectomy can probably benefit from a shorter course of more intense radiation therapy, a new study indicates.Hypofractionated radiation therapy — which provides a highe…
Learn MoreSurgeons Seeing More ‘Mutilating’ Hand Injuries With New Utility Terrain Vehicles
TUESDAY, Oct. 3, 2023 (HealthDay News) — A popular type of off-road vehicle known as a “side-by-side” has been linked to high rates of severe hand injuries, according to a new study.Side-by-sides are utility terrain vehicles (UTVs) designed to carry …
Learn MoreMore Progress Seen in Female Versus Minority Leadership Diversity in Medicine
WEDNESDAY, Sept. 27, 2023 (HealthDay News) — Some specialties have made significant improvements in academic medial leadership diversity since 2007, according to a study published online Sept. 25 in JAMA Network Open.Austin M. Meadows, from Henry For…
Learn MoreCirujanos realizan trasplante de corazón de cerdo genéticamente modificado en un segundo paciente
MARTES, 26 de septiembre de 2023 (HealthDay News) — Un segundo paciente humano ha recibido un corazón de cerdo genéticamente modificado mientras lucha contra los estragos de una enfermedad cardíaca en etapa terminal.El hombre de 58 años, Lawrence Fauc…
Learn MoreSurgeons Perform Transplant of Gene-Tweaked Pig Heart Into Second Patient
MONDAY, Sept. 25, 2023 (HealthDay News) — A second human patient has received a genetically altered pig heart as he battles the ravages of end-stage heart disease.The 58-year-old man, Lawrence Faucette, received the pig organ at the University of Mar…
Learn MorePremenopausal Bilateral Oophorectomy Linked to Chronic Conditions
TUESDAY, Sept. 19, 2023 (HealthDay News) — Women with a history of premenopausal bilateral oophorectomy (PBO), with or without concurrent or preceding hysterectomy, have more chronic conditions in late midlife, according to a study published online S…
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