Sleep Deprivation May Increase Risk for Systemic Lupus in Women

THURSDAY, Sept. 22, 2022 (HealthDay News) -- Lack of sleep is associated with an increased risk for systemic lupus erythematosus (SLE), particularly among women with concomitant depression or bodily pain, according to a study published online Sept. 12 in Arthritis Care & Research.
May Y. Choi, M.D., from Brigham and Women’s Hospital in Boston, and colleagues assessed whether sleep deprivation was associated with the risk for developing SLE. The analysis included data from 186,072 women participating in the Nurses' Health Study (NHS; 1986 to 2016) and NHSII (1989 to 2017).
The researchers found that chronic low sleep duration (no more than five hours/night versus more than seven to eight hours/night) was associated with increased SLE risk (adjusted hazard ratio [HR], 2.47), which persisted both in a four-year lagged analysis (adjusted HR, 3.14) and when adjusting for shiftwork, bodily pain, and depression (adjusted HR, 2.13). There was an additive relationship between low sleep duration and high bodily pain with an attributable proportion of 64 percent (HR for SLE with both risk factors, 2.97 versus neither). There was also an interaction noted between low sleep duration and depression with an attributable proportion of 68 percent (HR, 2.82).
"Our findings have implications for SLE prevention and the promotion of adequate sleep duration," the authors write.
Abstract/Full Text (subscription or payment may be required)
Related Posts
Survival Improves for Babies of America’s Youngest Moms
TUESDAY, April 11, 2023 (HealthDay News) -- The death rate among babies born to...
Accumulation of Visceral Adipose Tissue Linked to Lower Muscle Density
THURSDAY, Feb. 23, 2023 (HealthDay News) -- In men and women, age-related...
La viruela del mono no es la próxima pandemia, afirma una experta de la OMS
MARTES, 30 de mayo de 2022 (HealthDay News) -- Es probable que los cientos de...
Una infección anterior con la COVID no garantiza una buena inmunidad, según un estudio
MARTES, 31 de agosto de 2021 (HealthDay News) -- Usted tuvo COVID-19 y luego se...