Monofilament Suture Not Superior for Vaginal Cervical Cerclage

WEDNESDAY, Oct. 26, 2022 (HealthDay News) -- For women with a singleton pregnancy receiving vaginal cervical cerclage due to a history of pregnancy loss or premature birth, monofilament suture does not reduce the rate of pregnancy loss compared with suture thread, according to a study published in the Oct. 22 issue of The Lancet.
Victoria Hodgetts Morton, Ph.D., from the University of Birmingham in the United Kingdom, and colleagues conducted a pragmatic, randomized, superiority trial at 75 obstetric units in the United Kingdom. Women with a singleton pregnancy who received a vaginal cervical cerclage due to a history of pregnancy loss or premature birth or clinician concern based on ultrasound were randomly assigned to receive a monofilament suture or braided suture thread for their cervical cerclage (1,025 and 1,024, respectively).
The primary outcome was pregnancy loss, defined as miscarriage, stillbirth, or neonatal death in the first week of life, and was ascertained in 1,003 and 993 women in the monofilament suture group and the braided suture group, respectively. The researchers found that pregnancy loss occurred in 8.0 and 7.6 percent of women in the monofilament suture and braided suture groups, respectively (adjusted risk ratio, 1.05; 95 percent confidence interval, 0.79 to 1.40).
"Clinicians caring for women offered a vaginal cervical cerclage should use the result of this trial to facilitate discussions around the suture thread to optimize outcomes," the authors write.
Several authors disclosed financial ties to the biopharmaceutical and medical device industries.
Editorial (subscription or payment may be required)
Related Posts
Is Telemedicine Closing the ‘Race Gap’ in Primary Care?
FRIDAY, May 13, 2022 (HealthDay News) -- Here's one way in which the pandemic...
Las futuras madres necesitan la vacuna contra la tosferina, por el bien del bebé, según los CDC
MIÉRCOLES, 8 de febrero de 2023 (HealthDay News) -- Las mujeres embarazadas...
Vaccines Estimated to Have Prevented 19.8 Million COVID-19 Deaths
TUESDAY, June 28, 2022 (HealthDay News) -- During the first year of COVID-19...
FDA Panel Meets to Craft Future Vaccine Strategy
WEDNESDAY, April 6, 2022 (HealthDay News) -- An advisory panel to the U.S. Food...