Intra-Op Liposomal Bupivacaine Beneficial After Spinal Fusion in Scoliosis

FRIDAY, May 12, 2023 (HealthDay News) -- For adolescent idiopathic scoliosis (AIS) patients undergoing posterior spinal fusion (PSF), intraoperative liposomal bupivacaine (LB) infiltration is associated with lower total opioid consumption and shorter length of stay (LOS), according to a study published online May 1 in Spine.
Stuart Changoor, M.D., from St. Joseph's University Medical Center in Paterson, New Jersey, and colleagues analyzed postoperative oral and intravenous opioid consumption, ambulation distance, pain, nausea/vomiting, diazepam intake, and LOS to assess the effect of intravenous LB infiltration on postsurgical pain management in AIS patients in retrospective cohorts. Data were included for 119 consecutive patients with AIS who underwent PSF. Patients were categorized as those receiving LB as erector spinae block in addition to the standard postoperative pain management protocol (group A) and those who received only the standard postoperative pain management protocol (group B).
The researchers observed significantly lower total opioid consumption in group A versus group B (44.5 versus 70.2 mg). Group A had lower morphine use on postoperative day (POD) 0 and lower oxycodone use on PODs 1 and 2. Group A also had a higher proportion of patients who used only oral opioids (81 versus 41 percent). Seventy-nine percent of patients requiring intravenous opioids did not receive LB. Significantly more LB patients were discharged on POD 2 (55 versus 27 percent); shorter LOS was seen for group A. Postoperatively, group A ambulated farther. Pain scores, diazepam requirements, and nausea/vomiting did not differ between the groups.
"The use of a multimodal approach to pain management that includes LB is effective in opioid limitation and avoidance while improving ambulation postoperatively and decreasing LOS," the authors write.
Abstract/Full Text (subscription or payment may be required)
Related Posts
Un estudio apunta a que reducir las calorías diarias podría alargar la vida con salud
VIERNES, 11 de febrero de 2022 (HealthDay News) -- Una ligera reducción en su...
¿Beber muchos refrescos azucarados podría aumentar el riesgo de cáncer de hígado de una mujer?
MARTES, 14 de junio de 2022 (HealthDay News) -- Los refrescos y otras bebidas...
Combined AI, Mammography Texture Model Improves Breast CA Risk Prediction
TUESDAY, Aug. 29, 2023 (HealthDay News) -- Combining artificial intelligence...
Los empleados de restaurante enfermos quizá impulsen brotes de enfermedades transmitidas por los alimentos
MIÉRCOLES, 31 de mayo de 2023 (HealthDay News) -- Proveer licencia por...