Intervention Cuts Risk for AKI After Coronary Angiography

TUESDAY, Sept. 6, 2022 (HealthDay News) -- An intervention, including clinical decision support with audit and feedback, reduces the likelihood of acute kidney injury (AKI) among patients undergoing coronary angiography, according to a study published in the Sept. 6 issue of the Journal of the American Medical Association.
Matthew T. James, M.D., Ph.D., from the University of Calgary in Alberta, Canada, and colleagues examined whether a multifaceted intervention is effective for the prevention of AKI after coronary angiography or percutaneous coronary intervention (PCI) in a cluster randomized clinical trial conducted in Canada, which included invasive cardiologists at three cardiac catheterization laboratories. Cardiologists received educational outreach, computerized clinical decision support on contrast volume and hemodynamic-guided intravenous fluid targets, and audit and feedback during the intervention period. The intervention group included 31 physicians who performed 4,327 procedures among 4,032 patients undergoing nonemergency coronary angiography, PCI, or both, while the control group (preintervention period) included 34 physicians who performed 3,493 procedures among 3,251 patients.
The researchers found that the incidence of AKI was 7.2 and 8.6 percent during the intervention and control periods, respectively (odds ratio, 0.72). Of the 12 prespecified secondary outcomes, no significant differences were seen in eight outcomes. Reductions from the control to intervention period were seen in the proportion of procedures in which excessive contrast volumes were used (51.7 to 38.1 percent) and in the proportion of procedures in eligible patients in whom insufficient intravenous fluid was given (75.1 to 60.8 percent).
"Whether this intervention would show efficacy outside this study setting requires further investigation," the authors write.
Several authors disclosed financial ties to the pharmaceutical and health care industries.
Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Was this page helpful?
Related Posts
Age-Adjusted Rate of Alcohol-Induced Deaths Up From 2019 to 2020
FRIDAY, Nov. 4, 2022 (HealthDay News) -- From 2019 to 2020, the age-adjusted...
Health Highlights: Nov. 17, 2022
Could wireless earbuds help boost poor hearing? Apple earbuds proved their...
Flavored Nontobacco Oral Nicotine Products Widely Used by Teens
THURSDAY, Aug. 11, 2022 (HealthDay News) -- Flavored nontobacco oral nicotine...
Could Aspirin Cut Death Risk for Hospitalized COVID Patients?
THURSDAY, March 24, 2022 (HealthDay News) -- Something as simple as aspirin may...