Hypersensitivity Reactions to Gadolinium-Based Contrast Agents Studied
WEDNESDAY, May 4, 2022 (HealthDay News) -- The rate of hypersensitivity reactions (HSRs) to gadolinium-based contrast agents (GBCAs) is 0.4 percent, and premedication can reduce the risk for HSRs in patients with a history of acute or delayed HSRs, according to a study published in the May issue of Radiology.
Yoon Hae Ahn, M.D., from Seoul National University College of Medicine in South Korea, and colleagues examined the incidence of acute and delayed reactions to GBCAs in a retrospective analysis including all cases of HSRs to contrast media that occurred at a single center from July 1, 2012, to June 30, 2020.
The researchers found that 1,304 cases of HSRs (0.4 percent) were reported among the 331,070 magnetic resonance imaging examinations with GBCA exposure in 154,539 patients. Of the HSR cases, 1,178 were acute and 126 were delayed HSRs. In patients with a history of acute HSRs, premedication and changing the type of GBCA showed preventative effects (odds ratios, 0.7 and 0.2, respectively), while for patients with a history of delayed HSRs, only premedication significantly reduced the incidence of HSRs (odds ratio, 0.2). Those with a history of an HSR to iodinated contrast media had an increased risk for an HSR to GBCA (odds ratio, 4.6).
"As the most important preventive measure is avoidance of the culprit agent, a precise record of previously used GBCA should be kept for all patients," a coauthor said in a statement. "Physicians should discuss appropriate premedication strategies with their patients prior to magnetic resonance imaging procedures."
Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Related Posts
Mueren tres niños más de una misteriosa enfermedad del hígado
MARTES, 3 de mayo de 2022 (HealthDay News) -- Una grave enfermedad del hígado...
Flu Shot Season Is Here: Why You (and Your Kids) Need One
SATURDAY, Oct. 7, 2023 (HealthDay News) -- It’s time to get the flu shot....
Half of Parents Don’t Realize Impact of Screens on Kids’ Vision
MONDAY, July 18, 2022 (HealthDay News) -- Most parents are overlooking simple...
AHA News: Where You Live May Impact How Likely You Are to Take Your Blood Pressure Meds
FRIDAY, Sept. 9, 2022 (American Heart Association News) -- People who live in...