Link Between GI Issues, Internalizing Symptoms Studied in Autism
FRIDAY, April 29, 2022 (HealthDay News) — For children with autism spectrum disorder (ASD), a bidirectional relationship may exist between gastrointestinal (GI) issues and internalizing symptoms, according to a study published online April 20 in the …
Learn MoreCigarette Smoking Down for Adults With Behavioral Health Conditions
FRIDAY, April 29, 2022 (HealthDay News) — There were significant reductions in the prevalence of self-reported cigarette smoking among U.S. adults with major depressive episode (MDE), substance use disorder (SUD), or both between 2006 and 2019, accor…
Learn MoreMany Infants in WIC Program Not Getting Enough Vitamin D
FRIDAY, April 29, 2022 (HealthDay News) — A high proportion of infants in the Supplemental Nutrition Program for Women, Infants, and Children (WIC) are not meeting current vitamin D recommendations, according to a study published online March 11 in t…
Learn MoreDapagliflozin Well Tolerated in COVID-19 Patients, Regardless of eGFR
FRIDAY, April 29, 2022 (HealthDay News) — The effects of dapagliflozin are similar for hospitalized patients with COVID-19 with estimated glomerular filtration rate (eGFR) 2, according to a study published online April 28 in the Clinical Journal of the American Society of Nephrology.
Hiddo J. L. Heerspink, Ph.D., Pharm.D., from the University Medical Center Groningen in the Netherlands, and colleagues conducted a secondary analysis of the Dapagliflozin in Respiratory Failure in Patients with COVID-19 (DARE-19) trial, which randomly assigned 1,250 hospitalized patients with COVID-19 and cardiometabolic risk factors to dapagliflozin or placebo. Dual primary outcomes (time to new or worsened organ dysfunction or death, and a hierarchical composite end point of recovery) and key secondary kidney outcomes were assessed among those with baseline eGFR 2.
The researchers found that across eGFR subgroups, the effect of dapagliflozin versus placebo was consistent on the primary prevention outcome (hazard ratio, 0.80; 95 percent confidence interval, 0.58 to 1.10), primary recovery outcome (win ratio, 1.09; 95 percent confidence interval, 0.97 to 1.22), and the composite kidney outcome (hazard ratio, 0.74; 95 percent confidence interval, 0.50 to 1.07; P for interaction, 0.98, 0.67, and 0.44, respectively). The effects of dapagliflozin on acute kidney injury were also similar for those with eGFR 2 (hazard ratio, 0.71; 95 percent confidence interval, 0.29 to 1.77) and ≥60 mL/min per 1.73 m2 (hazard ratio, 0.69; 95 percent confidence interval, 0.37 to 1.29). In patients with eGFR 2, dapagliflozin was well tolerated.
“These new data from DARE-19 reinforce the safety of dapagliflozin in acutely ill patients hospitalized with COVID-19 even in those with reduced kidney function who are at particularly high risk of acute kidney injury,” Heerspink said in a statement.
Several authors disclosed financial ties to pharmaceutical companies, including AstraZeneca, which manufactures dapagliflozin and funded the study.
Learn MoreHigh Blood Pressure Now Affects 1 in Every 7 U.S. Pregnancies
FRIDAY, April 29, 2022 (HealthDay News) — Rates of high blood pressure among pregnant women in the United States are on the rise and now occur in at least one in seven hospital deliveries, a new government report warns.The overall rate of what are c…
Learn MoreRacial Differences Seen for Joint Replacement Care and Outcomes
FRIDAY, April 29, 2022 (HealthDay News) — Racial differences persist across the continuum of care among patients undergoing total joint arthroplasty (TJA), according to a study published in the April 15 issue of the Journal of Bone and Joint Surgery….
Learn MoreNew Omicron Subvariant Causing COVID-19 Spike in South Africa
FRIDAY, April 29, 2022 (HealthDay News) — A new Omicron subvariant called BA.4 appears to be driving a sharp rise in COVID-19 cases in South Africa, health experts say.The number of daily cases reported by the country has shot up from just a few hund…
Learn MoreAHA News: She Retired From Playing Football at 41, Had Heart Attack at 43
FRIDAY, April 29, 2022 (American Heart Association News) — Throughout every stage of her life, Tammy Spencer Bey has defined herself as an athlete.She played softball from a young age through high school. In college, Tammy was on a flag football team…
Learn MoreYour Dog’s Breed Has Little Influence on Behavior, Study Finds
FRIDAY, April 29, 2022 (HealthDay News) — For the past couple of centuries, humans have been breeding dogs to meet specific physical characteristics — to make Golden Retrievers fluffy, to make Rottweilers muscular, or to make Chihuahuas tiny.Dog enth…
Learn MoreCDC Reports First American With New Bird Flu, Says Risk to Public Low
FRIDAY, April 29, 2022 (HealthDay News) – The first U.S. case of bird flu in a human has been confirmed in Colorado, federal and state health officials reported Thursday.Still, the risk to the general public is low, the U.S Centers for Disease Control…
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