Time to Benefit Estimated for Intensive BP Control to Prevent Stroke
WEDNESDAY, Feb. 9, 2022 (HealthDay News) — About 1.7 years of more intensive hypertensive treatment would be needed to prevent one stroke per 200 older adults, according to research published online Feb. 9 in the Journal of the American Geriatrics Society.
Vanessa S. Ho, from California Northstate University in Elk Grove, and colleagues conducted a meta-analysis to estimate the time to benefit (TTB) for stroke prevention after initiation of more intensive hypertension treatment in adults aged 65 years or older. Data were abstracted from randomized controlled trials comparing standard to more intensive treatment groups among older adults. Data were included from nine trials, with 38,779 individuals.
The researchers found that for 200 persons receiving more intensive hypertensive treatment, 1.7 years were required to prevent one stroke. Across studies, there was heterogeneity; longer TTB was seen for studies focusing on tighter systolic blood pressure (SBP) control (SBP
“These results suggest that almost all older adults with hypertension would benefit from treatment,” the authors write. “For older adults with relatively well-controlled hypertension (i.e., SBP
Learn MoreTrametinib Slows Recurrent Low-Grade Serous Ovarian Carcinoma
WEDNESDAY, Feb. 9, 2022 (HealthDay News) — Trametinib may be a new option for standard-of-care treatment for recurrent low-grade serous ovarian carcinoma, according to a study published online Feb. 5 in The Lancet.David M. Gershenson, M.D., from the …
Learn MoreUpdated Brain Injury Guidelines Validated for Complicated mTBI
WEDNESDAY, Feb. 9, 2022 (HealthDay News) — Use of the 2018 updated Brain Injury Guidelines (uBIG) potentially could decrease the need for transfers of Canadian patients with complicated mild traumatic brain injury (mTBI), according to a study publish…
Learn MoreFour in 10 Adults Report Heart Symptoms During the Pandemic
WEDNESDAY, Feb. 9, 2022 (HealthDay News) — Four in 10 U.S. adults report experiencing at least one heart-related issue since the beginning of the COVID-19 pandemic, according to the results of a survey released Feb. 1 by the Cleveland Clinic.The onli…
Learn MoreBilateral Oophorectomy May Up Risk for Developing Dementia
WEDNESDAY, Feb. 9, 2022 (HealthDay News) — Bilateral, but not unilateral, oophorectomy is associated with an increased rate of subsequent dementia, according to a study published online Jan. 31 in Menopause.Cecilie S. Uldbjerg, from the University of…
Learn MoreLiving in Poor Neighborhood Tied to Worse Mitral Valve Repair Outcomes
WEDNESDAY, Feb. 9, 2022 (HealthDay News) — Neighborhood-level socioeconomic status (SES) significantly predicts mortality and repair rate in patients undergoing isolated mitral valve surgery for degenerative disease, according to a study presented at…
Learn MoreImproved Air Quality May Slow Cognitive Decline in Older Women
WEDNESDAY, Feb. 9, 2022 (HealthDay News) — Greater improvement in long-term air quality (AQ) in late life is associated with slower cognitive declines in older women, according to a study published online Feb. 3 in PLOS Medicine.Diana Younan, Ph.D., …
Learn MoreComputerized Adaptive Test May Help Assess Suicide Risk
WEDNESDAY, Feb. 9, 2022 (HealthDay News) — The Computerized Adaptive Test Suicide Scale (CAT-SS) can enhance personalized screening and assessment of suicide risk severity among U.S. veterans, according to a study published online Jan. 21 in PLOS ONE…
Learn MoreMethotrexate-Related AEs Profiled in Early Rheumatoid Arthritis
WEDNESDAY, Feb. 9, 2022 (HealthDay News) — Adverse events are common among patients during the first year of treatment with methotrexate for early rheumatoid arthritis, according to a study published online Jan. 25 in Rheumatology.Ahmad A. Sherbini, …
Learn MoreTwenty-Nine Novel Loci Identified for Acne Susceptibility
WEDNESDAY, Feb. 9, 2022 (HealthDay News) — Twenty-nine novel significant loci for acne have been identified, according to a study published online Feb. 7 in Nature Communications.Brittany L. Mitchell, Ph.D., from the QIMR Berghofer Medical Research I…
Learn More