Extra Weight in Midlife Has Later Health, Cost Effects
TUESDAY, March 22, 2022 (HealthDay News) — Being overweight in midlife is associated with long-term adverse health and economic consequences in older adulthood, according to a study published online March 15 in JAMA Network Open.Sadiya S. Khan, M.D.,…
Learn MoreAI Model Predicts Colorectal Cancer Risk in Younger Adults
TUESDAY, March 22, 2022 (HealthDay News) — Machine learning can use electronic health record (EHR) data to predict colorectal cancer (CRC) risk in adults 35 to 50 years of age, according to a study published online March 10 in PLOS ONE.
Hisham Hussan, M.D., from The Ohio State University in Columbus, and colleagues developed a prediction model using machine learning and EHR-derived factors to identify individuals aged 35 to 50 years who may benefit from early CRC screening. Analysis of the model’s effectiveness included 30 percent of 3,116 adults aged 35 to 50 at average risk for CRC who underwent colonoscopy between 2017 and 2020 at a single center, while the remaining 70 percent were used to develop the model.
The researchers found that all four machine learning models predicted CRC with higher discriminative ability versus the reference model (C-statistics [95 percent confidence intervals]: neural network, 0.75 [0.48 to 1.00] versus reference, 0.43 [0.18 to 0.67]; P = 0.07). Three of the four machine learning approaches (except for gradient boosting) predicted CRC or high-risk polyps significantly better than the reference model (regularized discriminant analysis, 0.64 [0.59 to 0.69] versus reference, 0.55 [0.50 to 0.59]; P
“Further development of our model is needed, followed by validation in a primary-care setting, before clinical application,” the authors write.
Learn MoreMany Youth Overdosing on Benzos, Stimulants Have Recent Rx
TUESDAY, March 22, 2022 (HealthDay News) — A considerable proportion of youth with overdoses involving benzodiazepines (BZDs) or stimulants have recent prescriptions for these medications, according to a study published online March 2 in Pediatrics.I…
Learn MoreCOVID-19-Associated Hospitalization Rate Up During Omicron
MONDAY, March 21, 2022 (HealthDay News) — COVID-19-associated hospitalization rates increased during the period of omicron predominance, with the lowest rates among vaccinated adults who had received a booster or additional dose, according to resear…
Learn MoreOphthalmologic Procedures Not Tied to Increased AMI Risk
MONDAY, March 21, 2022 (HealthDay News) — Ophthalmologic procedures performed in an outpatient setting do not appear to be associated with an increased risk for acute myocardial infarction (AMI), according to a study published online March 22 in the …
Learn MoreRisk for Shoulder Conditions Small After Vaccination in Deltoid Muscle
MONDAY, March 21, 2022 (HealthDay News) — There is a small absolute risk for shoulder conditions after intramuscular vaccination administered in the deltoid muscle, according to a study published online March 22 in the Annals of Internal Medicine.Che…
Learn MoreJergens Moisturizer Recalled Due to Bacteria Risk
MONDAY, March 21, 2022 (HealthDay News) — Certain lots of Jergens moisturizer have been recalled because they may be contaminated with bacteria that pose a risk to people with weakened immune systems.Pluralibacter gergoviae bacteria typically pose li…
Learn MoreProgress ID’d Toward Maternal, Neonatal Tetanus Elimination
MONDAY, March 21, 2022 (HealthDay News) — By December 2020, 80 percent of the 59 priority countries had achieved maternal and neonatal tetanus elimination (MNTE), according to research published in the March 18 issue of the U.S. Centers for Disease C…
Learn MoreFactors Associated With Nonresponse to FMT Identified in IBS
MONDAY, March 21, 2022 (HealthDay News) — For patients with irritable bowel syndrome (IBS), those who are male and/or have low Alistipes levels are more likely to be nonresponders to fecal microbiota transplantation (FMT), according to a study publis…
Learn MoreElobixibat Improves Constipation in Chronic Kidney Disease
MONDAY, March 21, 2022 (HealthDay News) — For patients with moderate- to end-stage chronic kidney disease, elobixibat is associated with improvement in constipation and lipid metabolism, according to a study recently published in Frontiers in Medicin…
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