Early Glycemic Control May Cut CV Risk in Type 2 Diabetes
WEDNESDAY, May 18, 2022 (HealthDay News) — Early control of glycated hemoglobin (HbA1c) may improve cardiovascular outcomes in type 2 diabetes, according to a study published online April 4 in Diabetes, Obesity and Metabolism.
Martin B. Whyte, Ph.D., from University of Surrey in the United Kingdom, and colleagues examined whether achieving early glycemic control and any subsequent glycemic variability was associated with any change in the risk for major adverse cardiovascular events (MACE). The analysis included 26,180 newly diagnosed patients (aged 25 years or older) with type 2 diabetes on or after Jan. 1, 2005, with HbA1c measurements at both diagnosis and after one year.
The researchers found that compared with those with HbA1c
“Our findings support the concept that effort must be made to achieve rapid metabolic normalization after the diagnosis of diabetes in those with a low propensity to hypoglycemia,” the authors write.
Several authors disclosed financial ties to pharmaceutical companies, including Eli Lilly, which funded the study.
Learn MoreObesity Linked to Increased Risk for Crohn Disease
TUESDAY, May 17, 2022 (HealthDay News) — Obesity, as measured by body mass index (BMI), is associated with an increased risk for Crohn disease (CD) but not ulcerative colitis (UC), according to a study published in the May issue of Clinical Gastroenterology & Hepatology.
Simon S. M. Chan, M.B., B.Chir., Ph.D., from the Norfolk and Norwich University Hospital National Health Service Trust in the United Kingdom, and colleagues conducted pooled analyses of data from five prospective cohort studies with validated anthropometric measurements for BMI and waist-hip ratio and other lifestyle factors to examine the association between obesity and CD and UC risk.
The researchers confirmed 563 incident cases of CD and 1,047 incident cases of UC among 601,009 participants with 10,110,018 person-years of follow-up. Compared with normal BMI (18.5 to 2), obesity (baseline BMI ≥30 kg/m2) was associated with increased CD risk. Each 5-kg/m2 increment in early adulthood BMI (age 18 to 20 years) was associated with a significant increase in CD risk. An increase in waist-hip ratio was associated with increased CD risk, but the association was not statistically significant. There were no associations observed between measures of obesity and UC risk.
“Our data implies that the growing burden of obesity is likely contributing to the increasing incidence of CD worldwide,” the authors write. “Future work should consider examining the precise mechanisms through which obesity may influence the etiopathogenesis of CD.”
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Learn MoreFDA Authorizes Pfizer Booster Shot for Children Ages 5 to 11 Years
TUESDAY, May 17, 2022 (HealthDay News) — A single booster dose of the Pfizer COVID-19 vaccine can be given to 5- to 11-year-olds, the U.S. Food and Drug Administration announced today.The third shot can be given at least five months after healthy chi…
Learn MoreFDA Expands Baby Formula Market to Foreign Suppliers
TUESDAY, May 17, 2022 (HealthDay News) — Dealing with a crippling shortage of infant formula that has many U.S. parents desperate, the U.S. Food and Drug Administration on Monday announced “increased flexibilities” in allowing foreign manufacturers t…
Learn MoreRare Cases of Monkeypox Diagnosed in Britain
TUESDAY, May 17, 2022 (HealthDay News) — Four men in England have been infected with a “rare and unusual” monkeypox virus.Investigators from the U.K. Health Security Agency are investigating the cases and whether there is any connection between the m…
Learn MoreBiden Signs Law Banning Sleep Products Tied to Infant Deaths
TUESDAY, May 17, 2022 (HealthDay News) — The manufacture and sale of products known as crib bumpers and sleep incliners — linked with more than 200 infant deaths in the United States — will be banned under a new law signed by President Joe Biden.”T…
Learn MoreIncreasing Impact of HPV Vaccination Seen in the United States
TUESDAY, May 17, 2022 (HealthDay News) — The impact of human papillomavirus (HPV) vaccination is increasing in the United States, with evidence of herd protection, according to a study published online May 17 in the Annals of Internal Medicine.Hannah…
Learn MoreNewly Certified General Internists Mainly Choose Hospital Practice
TUESDAY, May 17, 2022 (HealthDay News) — Newly certified general internists mainly choose hospital medicine as their career path, according to a study published online May 17 in the Annals of Internal Medicine.Bradley M. Gray, Ph.D., from the America…
Learn MoreAUA: Outcomes of Robotic, Open Cystectomy Compared in Bladder Cancer
TUESDAY, May 17, 2022 (HealthDay News) — For patients with nonmetastatic bladder cancer, robot-assisted radical cystectomy is associated with more days alive and out of the hospital within 90 days of surgery compared with open radical cystectomy, acc…
Learn MoreAlbuterol Plus Budesonide Cuts Exacerbations in Asthma
TUESDAY, May 17, 2022 (HealthDay News) — For patients with moderate-to-severe asthma, as-needed use of a fixed combination of albuterol and budesonide is associated with a lower risk for severe asthma exacerbations compared with as-needed use of albu…
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