Amino Acid Supplementation Beneficial After Fracture Fixation

MONDAY, March 28, 2022 (HealthDay News) -- For adults undergoing fracture fixation, conditionally essential amino acid (CEAA) supplementation is associated with a reduction in postoperative complications, according to a study published online March 14 in the Journal of Bone & Joint Surgery.
Nathan R. Hendrickson, M.D., from the University of Iowa in Iowa City, and colleagues conducted a prospective, randomized controlled trial (RCT) to examine the impact of CEAA supplementation on complications and skeletal muscle mass among adults after operative fixation of acute fractures. Four hundred adults were enrolled and randomly assigned to either standard nutrition or CEAA (200 participants to each).
The researchers found that overall complications were significantly lower for the CEAA group versus the control group (30.5 versus 43.8 percent; adjusted relative risk, 0.71). At six weeks, fat-free mass (FFM) decreased significantly in control subjects (−0.9 kg) and was maintained in CEAA subjects (−0.33 kg). At subsequent time points, this difference in FFM was not observed.
"Our results suggest that this inexpensive, low-risk intervention has considerable potential to improve outcomes after fracture fixation," the authors write. "This study will serve as the foundation for multicenter RCTs that are designed to assess the impact of CEAA nutrition supplementation in reducing complications and loss of functional muscle mass in high-risk populations."
Abstract/Full Text (subscription or payment may be required)
Related Posts
Worried About Omicron? Expert Offers Tips on Going Out Safely
https://consumer.healthday.com/b-1-14-worried-abou... Credit: HealthDay
La EPA propone unos estándares más estrictos para las emisiones de los grandes camiones
LUNES, 7 de marzo de 2022 (HealthDay News) -- El lunes, la Agencia de Protección...
Medtronic Expands Recall to Include More Than 463,000 Insulin Pumps
TUESDAY, Oct. 5, 2021 (HealthDay News) -- Medtronic has expanded a recall of its...
In Canada, Program That Supplies Safe Opioids to Addicts Is Saving Lives
TUESDAY, Sept. 20, 2022 (HealthDay News) -- As opioid overdose deaths continue...