Additional Biopsies After CRC Biopsy Not Tied to Metachronous CRC
THURSDAY, June 9, 2022 (HealthDay News) -- There is no significant association between metachronous cancer and biopsy of nontumor sites after biopsy of a primary colorectal cancer (CRC), according to a study published online May 26 in Clinical Gastroenterology and Hepatology.
Angela Y. Lam, M.D., from Kaiser Permanente San Francisco, and colleagues conducted a retrospective case-control study involving adults with an initial CRC diagnosed by colonoscopy between January 2006 and June 2018 who underwent curative resection. Cases developed a second primary (metachronous) CRC, which was diagnosed six months to four years after initial CRC, and were matched with up to five controls without a second CRC diagnosis.
The researchers found that 107 of the 14,119 patients diagnosed with an initial CRC during colonoscopy received a second CRC diagnosis. Data were included for 45 cases and 212 controls after exclusions for recurrent or synchronous CRC. Biopsy of nontumor sites after initial CRC biopsy was not significantly associated with the risk for metachronous CRC in the segment of the additional biopsy site.
"Metachronous cancers are rare after primary CRCs and are not associated with biopsy of nontumor sites after biopsy of the primary cancer," the authors write. "Although sample size cannot exclude any association, these clinical findings do not support iatrogenic tumor seeding as a common risk factor for metachronous CRC."
Abstract/Full Text (subscription or payment may be required)
Related Posts
Few Regret Undergoing Gender-Affirming Mastectomies
THURSDAY, Aug. 10, 2023 (HealthDay News) – For people who are transmasculine or...
El tratamiento para la depresión comienza a cambiar el cerebro en 6 semanas
MIÉRCOLES, 2 de noviembre de 2022 (HealthDay News) -- Una nueva investigación...
Unos compuestos comunes en la mayoría de máscaras faciales no son peligrosos, según un estudio
VIERNES, 1 de abril de 2022 (HealthDay News) -- Una tranquilizadora...
Role of Molecular Factors in BMI, Endometrial Cancer Link Studied
TUESDAY, April 19, 2022 (HealthDay News) -- Molecular traits may mediate the...